Ah, now that will depend on what you expect from your home, how many family members are living there, and their ages. And a lot of other things.
Do you have enough bathrooms for the number of people living in the home? If not, you can have a half-bath added or a full bath if there is room.
Is the home adequately heated? Does it need cooling in the summer, but doesn’t have any? consider updating to a heat pump; they both heat and cool, and with supplemental heating they will work great all year round.
Kitchens can be a force for change; too dark, too small, surface materials too worn? It may be time to update that space. You spend a lot of time in the kitchen, you deserve a pleasant, cheerful, efficient kitchen.
Exterior features that may need work are the roof, the deck, siding and windows. Weathering takes a toll on the exterior, some climates more so than others.
You can tackle any repairs and remodel features individually, there is no need to do it all at once! Be sure to do your research before selecting a contractor; you want to be sure that they will work well with you and that they do quality work. Friends who have had work done recently are your best resource to finding a great contractor; check also with your local BIAW and NAHB organizations, you can get more information on qualified contractors in your area from these great organizations. And remember, the lowest bid is not always the best one to select.